Link Search Menu Expand Document

Diabetes

Table of contents
  1. Types of Diabetes
    1. Type 1
    2. Type 2

Affects the Islets of Langerhans in the pancreas. Beta cells located on the Islets of Langerhans produce Insulin, which is responsible for:

  • Facilitating the uptake of glucose into cells
  • Glycogenesis (the conversion of glucose to glycogen for storage),
  • Stimulation of Lipogenesis (fatty acid and triglyceride synthesis)
  • Inhibiting both glycogenolysis and gluconeogenesis
  • Inhibiting the breakdown of fats into ketone bodies.
Glycogenesis
Glucose is converted to glycogen and stored in the liver when BSL are elevated
Glycogenolysis
Breakdown of glycogen stores to release glucose when our BSL levels are depleted
Gluconeogenesis
Creation of new glucose.
When all glycogen stores have been used, the liver can convert amino acids and glycerol to glucose when our BSL levels are depleted.

Types of Diabetes

Type 1

T1DM pathogenesis

Type 2

Type 2 DM pathogenesis


Back to top

Site licenced under CC BY-NC-SA 4.0 with thanks to Life in the Fast Lane and The Calgary Guide for their content and generosity in licencing for re-use